Explaining the Difference Between the Dermis and Subcutaneous Tissue | What Are Skin-Nourishing Injections That Target the Dermis?

Although both the dermis and subcutaneous tissue are located within the skin, they each play distinct roles. Understanding how the dermis—which is responsible for skin firmness and elasticity—functions will make it easier to choose the right cosmetic treatment for your specific skin concerns. In this article, we’ll explain the differences between the dermis and subcutaneous tissue, and provide a detailed overview of the characteristics and types of “skin-nourishing injections” that target the dermis directly.

Let's Learn About the Structure of the Skin

The structure of the skin is broadly divided into three layers: the “epidermis,” the “dermis,” and the “subcutaneous tissue,” with the epidermis being the outermost layer. The outermost layer of the epidermis is the stratum corneum, andThe thickness is approximately 0.01 to 0.03 mm, which is about the same as a single sheet of plastic wrap.。基本的に化粧品は表面の角質層までしか浸透しないため、肌表面のケアで真皮層まで美容成分を届けるのは難しいとされています。

それぞれの層には、以下のような役割があります。

The dermis forms the foundation of the skin

The dermis contains collagen, hyaluronic acid, elastin, and other components that help maintain the skin’s firmness and hydration. Therefore,When collagen, hyaluronic acid, and elastin decrease, the skin's underlying structure weakens, leading to wrinkles and sagging.. This is why the dermis is often referred to as the foundation of the skin.

For targeting the dermis, we recommend skin-nourishing injections!

To improve skin conditions such as wrinkles and dryness,It is important to target the dermis, which forms the foundation of the skin.That's right. Since the skin-rejuvenating injection is administered into the dermis, it provides a direct approach. By replenishing the hyaluronic acid and collagen lost with age and strengthening the skin's foundation, it is expected to improve skin texture.

Types of Skin-Nourishing Injections Available at Yayoi Clinic

ヤヨイクリニックで受けられる肌育注射の種類は6つあります。種類と成分をチェックしていきましょう。

〈ジュベルック〉
主成分：PDLLA（ポリ乳酸）・非架橋ヒアルロン酸

〈リジュラン〉
主成分：サーモンのDNAから抽出されるポリヌクレオチド

〈ハイドロ〉
主成分：3種類の分子量の異なるヒアルロン酸

〈プロファイロ〉
主成分：2種類の分子量の異なるヒアルロン酸

〈ボライトXC〉
主成分：架橋ヒアルロン酸

〈スネコス〉
主成分：非架橋ヒアルロン酸・6種のアミノ酸

If you want beautiful skin, you need to care for both the epidermis and the dermis

The dermis is often referred to as the foundation of the skin, butYou must not neglect the care of the outer layer that serves as the roof.. Use doctor-formulated skincare products to condition the epidermis and skin treatments to revitalize the dermis. Furthermore, skin-rejuvenating injections help rebuild the dermis, allowing you to achieve beautiful skin through this dual-pronged approach.

Get 30% OFF skin-nourishing injections when you sign up as a trial participant!

We are pleased to announce the launch of our Skin Rejuvenation Injection Select Plan! The Select Plan is designed for those who are unsure which treatment is right for them. During a consultation, a doctor will listen to your concerns and help you choose the most suitable treatment. As this is a special introductory offer, we’re offering a 30% discount off the regular price. Let’s work toward achieving clear, radiant skin that glows from within with Yayoi Clinic’s Skin Rejuvenation Plan.

For skin growth injections, go to YAYOI CLINIC

真皮は、肌のハリや弾力を支える大切な層です。肌育注射は真皮へ直接アプローチすることで、肌質改善やハリ・うるおいの向上を目指す治療です。
ヤヨイクリニックでは、6種類の肌育注射をご用意しており、お悩みや肌状態に合わせて適した薬剤をご提案しています。どの薬剤を選べばよいか迷っている方も、お気軽にご相談ください。

広島の美容皮膚科・美容内科・美容外科・アートメイク YAYOI CLINIC（ヤヨイクリニック）では、お肌、お身体、お顔のお悩み別に治療法をご紹介しています。
皆さまにより良い選択肢をご提案できますよう一人ひとりのお肌の状態を見極め、治療期間やご予算、ダウンタイムの許容範囲などご希望に合わせた治療方針を立案していく考えです。
お悩みのある方は、まずはカウンセリングにお越しください。

【施術の内容】ジュベルック
【施術回数の目安】
Fine wrinkles: 1-2 times per month
Skin texture improvement: about twice per month
Acne scars: about 3 times per month
*Depends on the condition of the skin.
【費用】1回¥55,000～149,800
【副作用・リスク】
Redness, swelling, and swelling at the injection site
【使用機器について】
JUVELEC's treatment includes procedures using domestically unapproved drugs or medical devices.
The medicines and medical devices used for treatment were imported from Japan under the judgment of our doctors. Please refer to the following for information on medicines and other items of concern for personal importation.
　　https://www.yakubutsu.mhlw.go.jp/individualimport/purchase/index.html
There are no other domestically approved drugs with the same ingredients or performance.
Information on safety, etc. in other countries
U.S. Food and Drug Administration (FDA)
Ministry of Food and Drug Safety of Korea (MFDS)
CE Medicines in Europe
Serious risks, side effects, etc. may not have been identified.
About the Adverse Reactions Relief System for Drugs
In the unlikely event of serious side effects, the drug is not covered by the government's Adverse Drug Reactions Relief System.

【施術の内容】リジュラン
【施術回数の目安】2〜3週間ごとに計3～4回/メンテナンスとして、半年に1回を推奨。
【費用】¥58,000〜¥204,000※部位・回数によって料金は異なります。
【副作用・リスク】疼痛・赤み・腫れ・内出血
【使用機器について】
Rejuran treatments include procedures using unapproved drugs or medical devices in Japan.
The medicines and medical devices used for treatment were imported from Japan under the judgment of our doctors. Please refer to the following for information on medicines and other items of concern for personal importation.
　　https://www.yakubutsu.mhlw.go.jp/individualimport/purchase/index.html
There are no other domestically approved drugs with the same ingredients or performance.
Information on safety, etc. in other countries
Serious risks, side effects, etc. may not have been identified.
About the Adverse Reactions Relief System for Drugs
In the unlikely event of serious side effects, the drug is not covered by the government's Adverse Drug Reactions Relief System.

【施術の内容】ハイドロ
【施術回数の目安】2週間ごとに3～4回
【費用】¥71,000～204,000円※部位・回数によって料金は異なります。
【副作用・リスク】
Tingling, itching, redness, and heat may occur for about 2 days after treatment.
Swelling may remain for 1-2 days and internal bleeding for about 7 days, but usually resolves spontaneously.
Depending on the individual and the injection site, the puffiness may remain for 1-3 days after treatment. It will settle naturally as the drug is diffused.
【使用機器について】
Hydro treatments include procedures using domestically unapproved drugs or medical devices.
The medicines and medical devices used for treatment were imported from Japan under the judgment of our doctors. Please refer to the following for information on medicines and other items of concern for personal importation.
　　https://www.yakubutsu.mhlw.go.jp/individualimport/purchase/index.html
There are no other domestically approved drugs with the same ingredients or performance.
Information on safety, etc. in other countries
Obtained European CE Mark[p1].
Serious risks, side effects, etc. may not have been identified.
About the Adverse Reactions Relief System for Drugs
In the unlikely event of serious side effects, the drug is not covered by the government's Adverse Drug Reactions Relief System.

【施術の内容】プロファイロ
【施術回数の目安】
Initial: 2 times at 1 month intervals
After the second time: once every six months
*The number of treatments depends on the skin age.
【費用】¥82,000～¥158,400※回数によって料金は異なります。
【副作用・リスク】注入部位の痛み、炎症、赤み、かゆみ、腫れ、内出血、体質によるアレルギー反応など
【使用機器について】
Profibro's treatment includes procedures using domestically unapproved drugs or medical devices.
The medicines and medical devices used for treatment were imported from Japan under the judgment of our doctors. Please refer to the following for information on medicines and other items of concern for personal importation.
　　https://www.yakubutsu.mhlw.go.jp/individualimport/purchase/index.html
There are no other domestically approved drugs with the same ingredients or performance.
Information on safety, etc. in other countries
Serious risks and side effects may not be evident.
About the Adverse Reactions Relief System for Drugs
In the unlikely event of serious side effects, the drug is not covered by the government's Adverse Drug Reactions Relief System.

【治療の内容】ボライト（架橋型ヒアルロン酸製剤の注入）
【治療期間および回数】1回毎
【費用】1本 ¥69,800
【リスク・副作用等】内出血、赤み、腫れ、浮腫、かゆみ、痛み、アレルギーなど
【未承認医療機器・未承認医薬品等を用いた治療について】
・本治療には国内未承認医薬品または医療機器を用いた施術が含まれます。
Information on safety, etc. in other countries
－ジュビダームビスタ®ボライトXCは、顔面や頸部の小ジワ等の表面の凹み修正及び皮膚状態の改善（保水性、弾力性等）を目的として、薬事承認を受けています。
－医療機器承認番号：30200BZX00389000
There is a possibility that serious risks, side effects, etc. have not been identified.
In the unlikely event of serious side effects, the drug is not covered by the government's Adverse Drug Reactions Relief Program.

【施術の内容】スネコス
【施術回数の目安】2週間に1回×3～4回（1クール）※治療内容によっても異なります。
【費用】¥128,000〜¥175,800※部位・回数によって料金は異なります。
【副作用・リスク】出血、赤み、腫れ、圧痛、疼痛、痒み、軽度/中程度のアザ、軽度の浮腫、内出血など
【使用機器について】
Snekos treatment includes the use of unapproved drugs or medical devices in Japan.
The medicines and medical devices used for treatment were imported by private individuals based on the judgment of the doctors at our clinic. Please refer to the following for information on medicines and other items of concern for personal importation.
　　https://www.yakubutsu.mhlw.go.jp/individualimport/purchase/index.html
There are no other domestically approved drugs with the same ingredients or performance.
Information on safety, etc. in other countries
The following certifications have been obtained
-The special ratio of amino acids in the drug has been patented internationally by an Italian development company.
-CE Mark Class III (European safety standard conformity approval)
About the Adverse Reactions Relief System for Drugs
In the unlikely event of serious side effects, the drug is not covered by the government's Adverse Drug Reactions Relief System.