Isotretinoin | YAYOI CLINIC

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Isotretinoin combined therapy

Name of treatment	Trifil x Subsision x Isotretinoin
Treatment period frequency	Tri-fill: once a month (about 3-5 times per course) Subcision: Once a month (1 course: 3-6 times) Isotretinoin: 5 months to less than 1 year
Treatment Time	Tri-fill and subsision: about 30 minutes each
Side Effects risk	Tri-fill: swelling, redness, subcutaneous emphysema, etc. Subsidence: internal bleeding, keloid constitution, rare thickening of the skin, etc. Isotretinoin: risk of miscarriage or malformation in pregnant women, dry skin and mucous membranes, depression, psychosis, self-injury, headache, rash, mild itching, desquamation, blepharitis, conjunctivitis, myalgia, arthralgia, rhabdomyolysis, decreased liver function, hair loss, dizziness, and nausea.
cost	Tri-fill: 96,800-423,500 yen (tax included)　 Subsicion: With injection (JUVELUX) usually 2cm x 2cm per area ¥11,000, without injection ¥22,000 (tax included) Isotretinoin: First time (including blood draw) 10mg,20mg ￥19,800, Second and subsequent times (including blood draw) 10mg,20mg ￥19,800

First time (including blood sampling)	10mg,20mg	19,800 Yen
After the 2nd visit (including blood sampling)	10mg,20mg	19,800 Yen
	40 mg	29,800 yen

*Treatment is not self-directed, but at the dosage indicated by the physician.

*The duration of treatment varies from person to person.

Time required for treatment	Included in consultation time. The time varies depending on whether or not blood is drawn.
Approximate number of treatments	One follow-up visit every month *The number of times varies from person to person depending on the symptoms.
Approximate duration of treatment	About 5 months to less than 1 year *There are individual differences depending on body weight, prescription amount, and skin condition.
Bathing and washing face	No restrictions
make	No restrictions
taboo	The following persons are not allowed to take this drug -Pregnant or possibly pregnant -Pregnant women who wish to conceive. -Lactating mothers -Persons under 15 years of age or growing taller than 15 years of age -People with a history of allergy to isotretinoin, vitamin A, or tretinoin preparations. -Those taking tetracyclines such as Minomycin and Vibramycin -People undergoing treatment for depression or mental illness. -People with liver dysfunction -High triglycerides and cholesterol -Vitamin A excess *Please ask your doctor for details.
precautions	...Some recent studies have ruled out a causal relationship between serious mental illness and isotretinoin. Pregnancy should be avoided during and for one month after taking the medication. If pregnancy should occur, stop taking the drug immediately and consult a physician. Since mild recurrence may occur after treatment is completed, treatment to prevent recurrence with topical agents, etc. is also necessary.
Side Effects/Risks	Risk of miscarriage and malformations in pregnant women, dry skin and mucous membranes, depression, psychosis, self-injury, headache, rash, mild itching, desquamation, blepharitis, conjunctivitis, myalgia, arthralgia, rhabdomyolysis, decreased liver function, hair loss, dizziness, and nausea, which are rare side effects except dry skin and mucous membranes.
Equipment used	Isotretinoin treatment involves the use of a domestically unapproved drug or medical device. The medicines and medical devices used for treatment were imported by private individuals based on the judgment of the doctors at our clinic. Please refer to the following for information on medicines and other items of concern for personal importation. 　　https://www.yakubutsu.mhlw.go.jp/individualimport/purchase/index.html There are no other domestically approved drugs with the same ingredients or performance. Information on safety, etc. in other countries -Approved by the U.S. and FDA. About the Adverse Reactions Relief System for Drugs In the unlikely event of serious side effects, the drug is not covered by the government's Adverse Drug Reactions Relief System.

address (e.g. of house)	〒730-0013 6F KMM Building, 11-12 Hacchobori, Naka-ku, Hiroshima City, Hiroshima Prefecture View in GoogleMap
Access	Hatchobori Station" and "Tatemachi Station" of Hiroshima Electric Railway 2 minutes walk from