Kiko Kono, M.D.
Profile
Graduated from Kawasaki Medical School. Worked as a dermatologist for about 20 years at core hospitals. After many years of experience and achievements, he became a cosmetic dermatologist. His practice style is to examine the skin thoroughly and pursue what is happening where on the skin and approach the problem. Her specialties include customized treatment, laser treatment, Botox, and skin growth injections. In her private life, she is a mother of two children.
Plureal is a type of skin-rejuvenating injection that uses ingredients extracted from salmon and trout. It has obtained the “CE Mark,” which is awarded to products that comply with safety standards based on EU regulations, and is a cosmetic medical treatment that is gaining attention in Hiroshima as well. In this article, we’ve also summarized the features of YAYOI CLINIC, a cosmetic dermatology clinic in Hiroshima that offers Plurial. If you’re wondering, “How long is the downtime for Plurial?” or “Is it okay to choose a clinic just because it’s cheap?”, please use this as a reference.
What Is Plural? An Explanation from Yayoi Clinic in Hiroshima
First, I’ll explain the Plural treatment in detail.
■Purlial's Ingredients and How It Works
"Plural" means,A type of skin-nourishing injection that works from within the skin to promote a healthy complexion. Like REJURAN®, it is used as a treatment aimed at improving skin quality. At Yayoi Clinic in Hiroshima, which offers Pluryal® treatments, the clinic uses the Pluryal® DENSIFIER series of injectables.Mainly composed of polynucleotides extracted from salmon and troutとしており、EUの法令に基づく安全性および性能基準を満たした製品にのみ付けられる「CEマーク」を取得。肌の赤みや酒さ（しゅさ）などの悩みに、内側からアプローチします。
広島のヤヨイクリニックでは、以下のPluryal®製剤を使用しています。
| Pluryal® SILK
（プルリアル シルク） |
A formula that is expected to be effective in reducing dark circles and fine lines, as well as improving skin texture. It enhances the skin’s ability to retain moisture, leaving it supple and firm. |
| Pluryal® Densify
（プルリアル デンシファイ） |
This formulation is designed to address concerns such as enlarged pores, skin redness, wrinkles, and overall skin texture. It contains hyaluronic acid and mannitol, and is particularly effective for reducing skin redness. |
| Pluryal® BIOSCULPTURE
（プルリアル バイオスカルプチャー） |
This product is designed to address wrinkles and skin depressions. It helps minimize the appearance of wrinkles and gives you a more defined, refined facial appearance. |
■Differences from Conventional Cosmetic Injections
Plural is a type of skin-nourishing injection that infuses beneficial ingredients into the skin to improve its condition.Due to its ability to act on skin tissue and cells, it is expected to improve and repair skin conditionYes, it is possible. In recent years, it has been gaining attention—particularly in Europe—as an injectable treatment that works from within the skin.
Expected Effects and Duration of Plural
Next, Yayoi Clinic, a cosmetic dermatology clinic in Hiroshima, explains the benefits of Plural.
■Restores the skin to a healthy condition
Pural is a treatment that delivers nutrients to the dermis—the key to healthy skin—and helps improve the skin's condition.It is expected to target skin functions that tend to decline with age and promote collagen production.Yes, you can. By following an age-appropriate skincare routine, you can achieve a healthy-looking complexion.
■ Also recommended for those concerned about rosacea or redness
Prurial is a formulation with high antioxidant properties. As a result, it is effective in addressing skin redness and inflammation. This treatment is also recommended for addressing skin concerns such as rosacea and redness.
■Estimated Timeframe for Noticing Changes from Plural
Although the effects of Plural may vary from person to person,Generally, most people begin to notice a difference after about 3 to 4 weeks.I suppose so. Please note that at Yayoi Clinic, we define a “course” as three treatments, and we recommend that you visit the clinic once every 2 to 3 weeks.
Precautions When Undergoing a Plural Treatment
PluReal treatments are expected to be effective in reducing various skin concerns, such as wrinkles, sagging, and redness. However, there are also some precautions to keep in mind. Below, Yayoi Clinic in Hiroshima explains the key points to be aware of when undergoing PluReal treatment.
■Preparation before treatment
Before the procedure, you will need to remove your makeup and wash your face. After that, an anesthetic cream will be applied to the treatment area and left on for about 30 minutes. If you are sensitive to pain, please discuss this with the doctor or counselor during your preliminary consultation. During the consultation, we will listen to your concerns, andAfter determining whether the Plural treatment is right for you, we will propose a planI will do so.
なお、以下に当てはまる方はプルリアルの施術を受けられないので注意が必要です。
- Pregnant or nursing mothers
- People with autoimmune diseases
- People with allergies to fish or fish roe
- Individuals with a history of hypersensitivity to Plural's medications
In addition, we recommend that individuals with atopic dermatitis, a tendency to develop keloids, heart disease, or epilepsy consult thoroughly with their doctor before undergoing treatment and make a careful decision.
■Post-Treatment Precautions
Pluリアル treatments vary depending on the area and scope of the treatment, butTakes about 20 minutesPlease do so. Afterward, please try to avoid friction as much as possible. You may wash your face starting on the day of the treatment, and you may apply makeup starting the day after the treatment. Please refrain from drinking alcohol, smoking, and strenuous exercise. Also, please avoid massaging the treated area for about one week after the procedure, and refrain from undergoing any highly stimulating cosmetic treatments for about two weeks afterward.
■Risks Associated with the Procedure
The following risks are associated with the Plural treatment.
- Post-procedure bleeding
- swelling
- blush
- Swelling, itching
- Hematoma, etc.
The pharmaceuticals and medical devices used in our treatments are selected by the physicians at Yayoi Clinic following careful consideration. Some of the agents used in Plural treatments are not approved in Japan. While all products have obtained European CE certification, there are no approved drugs in Japan with the same active ingredients or performance characteristics.
For consultations regarding Plural, visit Yayoi Clinic in Hiroshima
If you are considering a Plural treatment in Hiroshima, please consider Yayoi Clinic, a cosmetic dermatology practice, as one of your options. Finally, here are some highlights of Plural treatments at Yayoi Clinic.
■ Unique Features Designed to Reduce Pain
Since Plural is a treatment that involves inserting needles into the skin, many people are concerned about pain. At Yayoi Clinic, we perform the procedure with pain management in mind, using anesthesia and the doctor’s expertise. Additionally, to reduce the discomfort during the injection,They’ve also implemented their own unique innovations, such as introducing the “Buru Buru Pen,”We are doing that.
■The Select Plan: Recommendations Tailored to Your Skin Condition
At Yayoi Clinic, our doctors assess each patient’s skin condition before recommending the appropriate treatment. This “Skin Care Injection Select Plan” will help you achieve your ideal skin condition more easily.
■Can be combined with other plans
肌育注射セレクトプランでは、定額制の肌管理パーソナライズプランと組み合わせてプルリアルを受けることができます。肌管理と肌育を掛け合わせ、さらなる美肌へ近付けられるでしょう。
■ Conclusion.
プルリアルは、肌の内側からアプローチする肌育注射の一種です。若々しい肌印象を目指しながら、肌の赤みや酒さなどの悩みにも配慮したケアが可能です。ただし、施術にはリスクが伴うため、不安な要素がある場合は、カウンセリングで医師にご相談ください。プルリアルを広島のヤヨイクリニックで受けて、理想の肌印象を目指してみませんか。
広島の美容皮膚科・美容内科・美容外科・アートメイク ヤヨイクリニック（YAYOI CLINIC）では、お肌、お体、お顔のお悩み別に治療法をご紹介しています。
皆さまにより良い選択肢をご提案できますよう一人ひとりのお肌の状態を見極め、治療期間やご予算、ダウンタイムの許容範囲などご希望に合わせた治療方針を立案していく考えです。
お悩みのある方は、まずはカウンセリングにお越しください。
■Related Articles Recommended for You
【施術の内容】プルリアル
【施術回数の目安】2～3週間に1回（1クール：3回程度）※治療間隔は肌状態によって異なります。
【費用】¥71,000～204,000円※部位・回数によって料金は異なります。
【副作用・リスク】処置後の出血、浮腫、腫れのない紅斑、赤み、腫れ、かゆみ、血腫、圧痛など
【使用機器について】
Pluryal treatments include procedures using domestically unapproved drugs or medical devices.
The medicines and medical devices used for treatment were imported from MD Skin Solutions, Inc. under the judgment of our doctors.
There are no other domestically approved drugs with the same ingredients or performance.
Information on safety, etc. in other countries
-All products are CE certified in Europe.
About the Adverse Reactions Relief System for Drugs
-In the unlikely event of serious side effects, the drug is not covered by the government's Adverse Drug Reactions Relief Program.
