Kiko Kono, M.D.
Profile
Graduated from Kawasaki Medical School. Worked as a dermatologist for about 20 years at core hospitals. After many years of experience and achievements, he became a cosmetic dermatologist. His practice style is to examine the skin thoroughly and pursue what is happening where on the skin and approach the problem. Her specialties include customized treatment, laser treatment, Botox, and skin growth injections. In her private life, she is a mother of two children.
Are you considering getting Rejuran injections in Hiroshima? Rejuran injections are a skin-rejuvenating treatment originating in South Korea, with salmon-derived polynucleotides (PN) as their main ingredient. This treatment enhances the skin’s natural vitality to help you achieve a healthy, radiant complexion. In this article, YAYOI CLINIC in Hiroshima will explain the basics of Rejuran injections, the procedure flow, and key points to keep in mind before and after treatment. If you’re interested in Rejuran injections, please use this as a reference.
What Is Rejuran? An Explanation from Yayoi Clinic in Hiroshima

For those wondering, “What is a Rejuran injection?” or “I want to know the effects of a Rejuran injection,” Yayoi Clinic in Hiroshima explains all about Rejuran.
■ Rijuran's Ingredients and Mechanism of Action
Rejuran is,A skin-nourishing injection developed in South Korea, with salmon-derived polynucleotides (PN) as its main ingredientIt is expected to stimulate the skin's natural functions and help achieve healthy, firm, and radiant skin.Works on fibroblasts—the building blocks of the skin—to support the production of collagen and hyaluronic acid. It also improves blood circulation and has anti-inflammatory properties, supporting skin health from the inside out.
■Differences from Conventional Cosmetic Injections
Rejuran and other cosmetic injections,The approach to skin care is different.. First, hyaluronic acid injections are a treatment in which the substance is injected under the skin in areas where a lack of volume is a concern to address wrinkles and sagging. While changes are often noticeable immediately after the procedure, the effects gradually fade. Botox injections, on the other hand, use botulinum toxin (type A) to relax muscle activity. They can help alleviate teeth grinding and treat or prevent expression lines, and patients typically notice results relatively sooner than with Rejuran.
■Expected Effects and Duration
リジュランは、線維芽細胞を活性化させ、目の周りの小ジワやくすみ・青クマ、ニキビ痕のケアに役立つとされています。
リジュランの効果はいつから出るのか、持続期間はどのくらいなのか気になる方もいるでしょう。リジュランには、即効性がないものの、You can start to see results 2 to 3 weeks after the treatment....will happen. Also, while the duration of the effects varies depending on skin type and lifestyle,A few months to about half a yearIt is.
実際に、「リジュランの施術をしたけれど効果ない」と感じた方がいるかもしれません。それは、リジュランには即効性がなく、施術後2~3週間で変化が現れることが一般的だからです。また、肌状態によっては、すぐに変化を実感しにくい場合もあります。特に健康な肌の場合、目に見える変化が少なく感じることがありますが、定期的に施術を行うことで、肌の質感が改善されることが期待できます。
Indications for Rejuran Injections and Expected Results
What kind of results can you expect from Rejuran injections? We’ll explain each one below.
■Fine Lines and Dark Circles Around the Eyes
Rejuran is an injectable treatment that reduces the appearance of fine lines caused by dryness and smooths the skin. When Rejuran is injected, it promotes skin renewal and stimulates the production of collagen, hyaluronic acid, and other substances that help maintain the skin’s moisture. As a result,It restores firmness and elasticity to the skin, making fine lines caused by dryness less noticeable.。
また、リジュランは、血行不良による目の下のクマ(青クマ)にも効果が期待できます。リジュラン注射をすることで、Targets the cells under the eyes to promote blood flow. Furthermore, by supporting the functions of collagen and hyaluronic acid, you can achieve a brighter, more voluminous eye area.
■ Acne Scars & Pore Care
Rejuran injections are,It normalizes skin turnover and restores the skin's barrier function.。皮脂の過剰な分泌をコントロールすることで、開きがちな毛穴の引き締めも目指せます。そのため、毛穴の目立ちや繰り返す肌荒れに悩む方にとっても、適した選択肢といえるでしょう。
さらに、リジュラン施術を繰り返すことで、肌にツヤとなめらかさを感じるように。肌全体のハリ感が整い、ニキビ痕も目立ちにくくなります。
■ Addressing Dullness and Skin Texture
Polynucleotide, the main ingredient in Rejuran, is expected to help revitalize cells. As collagen is produced and skin turnover is promoted, the skin’s texture becomes more even and moisturized.As skin turnover normalizes, dullness is reduced and skin brightness improvesI will do so.
What You Should Know Before Getting Rejuran Injections in Hiroshima

Before getting a Rejuran injection, we’ll explain what you need to know—including the procedure and aftercare—using Yayoi Clinic in Hiroshima City as an example.
Treatment flow and time required
リジュラン注射の施術の流れを説明します。広島のヤヨイクリニックでは、初めに肌悩みや治療の希望を伺うカウンセリングを実施。リジュラン注射に対して疑問や不安があれば、カウンセリングの際に相談しておきましょう。肌状態を診察し、リジュランが適しているか確認した後、適切な治療法を提案します。
施術前は、肌を清潔な状態に整えるためにクレンジングと洗顔をお願いしております。希望の注射部位を消毒し、細い注射針を用いてリジュランを注入。注入時の痛み軽減のため、麻酔テープや局所麻酔もご用意しています。なお、別途麻酔代が必要です。注入後、止血を確認して施術終了です。施術時間は、注射部位にもよりますがApprox. 15 to 30 min.The first two are the following.
■Aftercare and Precautions
Since Rejuran is sometimes administered around the eyes or under the eyes, some people may be concerned about downtime. Because the solution is injected into the skin, the injection sites may swell slightly, butIn most cases, symptoms subside within a few hours to a day.. In addition, swelling, redness, or bruising may occur in the treated area—such as under the eyes—but these symptoms typically subside within 2 to 3 days, or at most about a week. Since the formulation is well-tolerated by the skin,Relatively short downtime、日常生活に影響を与えにくいのが特徴です。症状が長引く場合や、不安な点がある場合は医師に相談しましょう。
アフターケアとしては、施術当日からシャワーや入浴は可能ですが、長時間の入浴は避けましょう。施術後12時間はメイクができないため注意が必要です。また、施術から1~2週間後は、紫外線対策や保湿を心がけ、患部に触れず摩擦を避けてください。
For consultations on Rejuran injections, visit Yayoi Clinic in Hiroshima
リジュラン施術を行う広島のヤヨイクリニックでは、東京銀座のBIANCA CLINIC直伝の痛みに配慮された方法を導入しています。従来のリジュラン注射に対して、痛みが不安な方にもおすすめです。
目元には、リジュランシリーズの中で最もやわらかく、目の周りの小ジワケアに適したリジュランiを使用しています。目元への使用を想定した製剤で、皮膚の薄い目元にもなじみやすいよう調整されており、血管への配慮が必要な部位にも使いやすい点が特徴です。
■ Conclusion.
リジュランの施術を広島で受けたい方に向け、期待される効果や持続期間、施術前後の注意点などを解説しました。リジュランは、肌本来の力を高めながら健康的でハリのある肌に導く肌育注射です。目周りの小ジワや青クマをケアしたい、目元にハリを出したい、くすみが気になるという方は、ヤヨイクリニックまでお気軽にお問い合わせください。
広島の美容皮膚科・美容内科・美容外科・アートメイク ヤヨイクリニック(YAYOI CLINIC)では、お肌、お体、お顔のお悩み別に治療法をご紹介しています。
皆さまにより良い選択肢をご提案できますよう一人ひとりのお肌の状態を見極め、治療期間やご予算、ダウンタイムの許容範囲などご希望に合わせた治療方針を立案していく考えです。
お悩みのある方は、まずはカウンセリングにお越しください。
■Related Articles Recommended for You
【施術の内容】リジュラン
【施術回数の目安】2〜3週間ごとに計3~4回/メンテナンスとして、半年に1回を推奨。
【費用】¥58,000〜¥204,000※部位・回数によって料金は異なります。
【副作用・リスク】疼痛・赤み・腫れ・内出血
【使用機器について】
Rejuran treatments include procedures using unapproved drugs or medical devices in Japan.
The medicines and medical devices used for treatment were imported from Japan under the judgment of our doctors. Please refer to the following for information on medicines and other items of concern for personal importation.
https://www.yakubutsu.mhlw.go.jp/individualimport/purchase/index.html
There are no other domestically approved drugs with the same ingredients or performance.
Information on safety, etc. in other countries
Serious risks, side effects, etc. may not have been identified.
About the Adverse Reactions Relief System for Drugs
In the unlikely event of serious side effects, the drug is not covered by the government's Adverse Drug Reactions Relief System.



