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Aesthetic dermatology, cosmetic medicine, cosmetic surgery, and art make-up in Hiroshima, Japan YAYOI Clinic | 9:00-18:00 (irregular holidays)

What’s the Difference Between PDRN and PN? Who Should Use Them? A Comprehensive Guide to Their Features

supervising physician

Kiko Kono, M.D.

Profile
Graduated from Kawasaki Medical School. Worked as a dermatologist for about 20 years at core hospitals. After many years of experience and achievements, he became a cosmetic dermatologist. His practice style is to examine the skin thoroughly and pursue what is happening where on the skin and approach the problem. Her specialties include customized treatment, laser treatment, Botox, and skin growth injections. In her private life, she is a mother of two children.

Both PDRN and PN are ingredients derived from salmon. In this article, we’ll introduce a treatment that’s perfect for those who want to maintain youthful-looking skin as they age. If you’ve ever wondered, “How effective is PDRN serum, really?” or “When do the effects of salmon injections start to show?”, be sure to check this out.

What Are PDRN and PN? Let’s Take a Look at Their Characteristics and Differences

PDRNとPNとは

PDRN (polydε-ribonucleotide) and PN (polynucleotide) are both ingredients derived from salmon.Expected to support skin cell regenerationCan be done.

PDRNとPNは、人間のDNAに非常に近い構造で、アレルギー反応や副作用が起きにくい特徴があります。It is expected to help promote collagen production and improve overall skin conditionI am sure you will.

Comparison Table of PDRN and PN

Comparison Table of PDRN and PN

PDRN has a low-molecular-weight structure, andIt penetrates relatively quickly to every corner of the skin特徴があります。保湿や弾力アップ、くすみを抑えて明るい肌へと導いてくれるでしょう。ヤヨイクリニックでは、リジュランブースターとして活用しており、ポテンツァやダーマペンの導入として使用しています。

一方、PNは高分子である特徴があり、比較的ゆっくりと肌に届く性質があります。スピードが遅いものの、One advantage is that the effects tend to last a long timeです。肌の再生を促し、シワが目立ちにくい弾力がある健やかな肌が目指せます。ヤヨイクリニックでは肌育注射として活用。リジュラン、リジュランi、プルリアルデンシファイで使用しています。

Features of PDRN | Rapid Penetration to Every Corner of the Skin

PDRNの特徴

PDRN is a type of DNA fragment extracted from salmon sperm. Its main effects are as follows:

  • For Youthful-Looking Skin
  • Improve skin condition
  • Anti-inflammatory effects
  • Skin tone enhancement

Features of PN | Long-Lasting Effects

PNの特徴

PN is a type of DNA fragment extracted from salmon testicles. When applied to the skin, it is expected to provide the following benefits.

  • Increased skin elasticity
  • Reduces sebum production
  • Refine the texture
  • Achieve firm, youthful-looking skin

Who Should Consider PDRN and PN?

PDRNとPNがおすすめの人

If any of the following apply to you, we recommend PDRN or PN.

  • I'm concerned about skin redness and inflammation
  • I want to have clear, radiant skin
  • I want to achieve a youthful-looking eye area
  • I want to improve dullness and uneven skin tone
  • I want to have naturally youthful skin
  • My skin looks dull
  • I want to improve my skin texture and skin conditions

However, all procedures carry some risk. We recommend starting by consulting with a cosmetic clinic.

For PDRN and PN, visit YAYOI CLINIC

PDRNとPNは、どちらもサーモン由来の成分ですが特徴や効果が異なります。特徴や違いを知り、ご自身の理想に合った方法を見つけてください。

広島の美容皮膚科・美容内科・美容外科・アートメイク YAYOI CLINIC(ヤヨイクリニック)では、お肌、お体、お顔のお悩み別に治療法をご紹介しています。
皆さまにより良い選択肢をご提案できますよう一人ひとりのお肌の状態を見極め、治療期間やご予算、ダウンタイムの許容範囲などご希望に合わせた治療方針を立案していく考えです。
お悩みのある方は、まずはカウンセリングにお越しください。

【施術の内容】リジュラン
【施術回数の目安】2〜3週間ごとに計3~4回/メンテナンスとして、半年に1回を推奨。
【費用】¥58,000〜¥204,000※部位・回数によって料金は異なります。
【副作用・リスク】疼痛・赤み・腫れ・内出血
【使用機器について】
Rejuran treatments include procedures using unapproved drugs or medical devices in Japan.
The medicines and medical devices used for treatment were imported from Japan under the judgment of our doctors. Please refer to the following for information on medicines and other items of concern for personal importation.
  https://www.yakubutsu.mhlw.go.jp/individualimport/purchase/index.html
There are no other domestically approved drugs with the same ingredients or performance.
Information on safety, etc. in other countries
Serious risks, side effects, etc. may not have been identified.
About the Adverse Reactions Relief System for Drugs
In the unlikely event of serious side effects, the drug is not covered by the government's Adverse Drug Reactions Relief System.

【施術の内容】ポテンツァ
【施術回数の目安】4~6週間おきに3回~(肝斑は2週間おき)
※施術回数は、施術内容によって異なります。
【費用】1回 ¥54,780~¥104,500
【施術期間の目安 】3~5ヶ月程度
【副作用・リスク】
Infection, hyperpigmentation, folliculitis, erythema
After the procedure, the pores may become blocked due to inflammation or swelling, and temporary acne may develop or worsen.
Depending on the treatment, bleeding may occur.
Swelling and redness may occur after the procedure.
Please note that effects may vary from person to person. Also, depending on the area to be treated, some patients may not achieve outstanding results.
【使用機器について】
Treatment of potenza includes procedures using domestically unapproved drugs or medical devices.
The medicines and medical devices used for treatment were imported from Jeisys Medical Inc. under the judgment of our doctors. Please refer to the following for information on drugs and medical devices that should be imported by individuals.
  https://www.yakubutsu.mhlw.go.jp/individualimport/purchase/index.html
There are no other domestically approved drugs with the same ingredients or performance.
Information on safety, etc. in other countries
The following certifications have been obtained
-MFDS(2019.01)
About the Adverse Reactions Relief System for Drugs
In the unlikely event of serious side effects, the drug is not covered by the government's Adverse Drug Reactions Relief System.

【施術の内容】ダーマペン4
【施術回数の目安】2~4週間おきに1回、または6~8週間に1回(1クール:3~5回)
*The treatment interval depends on the degree of bleeding.
【費用】1回 ¥31,800~¥36,800
【副作用・リスク】
Redness and tingling may occur, but will generally subside within 1 to 2 days.
Symptoms such as peeling, internal bleeding, and swelling may appear for 7-10 days.
In rare cases, old keratin may peel off, but please be careful not to peel it off forcibly.
【使用機器について】
Dermapen4 treatment involves the use of a domestically unapproved drug or medical device.
The drugs and medical equipment used for treatment were purchased from PRSS.Japan, Inc. under the judgment of our doctors.
There are no other domestically approved drugs with the same ingredients or performance.
Information on safety, etc. in other countries
The following certifications have been obtained
ISO 13485
CE Standard
About the Adverse Reactions Relief System for Drugs
In the unlikely event of serious side effects, the drug is not covered by the government's Adverse Drug Reactions Relief System.

【施術の内容】プルリアル
【施術回数の目安】2~3週間に1回(1クール:3回程度)※治療間隔は肌状態によって異なります。
【費用】¥71,000~204,000円※部位・回数によって料金は異なります。
【副作用・リスク】処置後の出血、浮腫、腫れのない紅斑、赤み、腫れ、かゆみ、血腫、圧痛など
【使用機器について】
Pluryal treatments include procedures using domestically unapproved drugs or medical devices.
The medicines and medical devices used for treatment were imported from MD Skin Solutions, Inc. under the judgment of our doctors.
There are no other domestically approved drugs with the same ingredients or performance.
Information on safety, etc. in other countries
-All products are CE certified in Europe.
About the Adverse Reactions Relief System for Drugs
-In the unlikely event of serious side effects, the drug is not covered by the government's Adverse Drug Reactions Relief Program.

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